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RESEARCH LITERATURE
The Research Literature database was created and funded by the Florida Wildflower Foundation. Use the search features below to find scientific articles on native wildflowers that are commercially available or used in restoration projects.
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Antimycobacterial natural products: synthesis and preliminary biological evaluation of the oxazole-containing alkaloid texaline
Author(s): A. C. Giddens, H. I. M. Boshoff, S. G. Franzblau, C. E. Barry and B. R. Copp
Month: Oct
Year: 2005
Publication Type: Article
Journal: Tetrahedron Letters
Volume: 46
Issue: 43
Pages: 7355-7357
Article Topic(s): Medicinal chemistry
Research Setting(s): Laboratory
Species Referenced: Amyris elemifera (Sea torchwood),
Abstract
Discusses the synthesis of texaline, an antimycobacterial alkaloid isolated from Amyris elemifera as a potential source of new drugs to treat tuberculosis. Texaline was found to inactive in the assays done in this study but simpler diaryloxazoles were identified as potential lead compounds.Suggested Citation
A. C. Giddens, H. I. M. Boshoff, S. G. Franzblau, C. E. Barry and B. R. Copp. "Antimycobacterial natural products: synthesis and preliminary biological evaluation of the oxazole-containing alkaloid texaline." Tetrahedron Letters 46.43 (2005): 7355-7357.Go back